Urology for Practice - Latest articles
Results 61 to 90 of 216:
Metabolic syndrome nad urinary track disordersFrom the boundary of urology
prof. MUDr. Miroslav Merta, CSc.
Urol. praxi. 2025;26(1):46-50 | DOI: 10.36290/uro.2025.024 
Metabolic syndrome (MetS) is a complex unit of various metabolic disorders, including abdominal obesity, dyslipidemia, elevated blood pressure and increased fasting glycemia, which act in mutual interplay as important risk factors for multiple diseases, including disorders of urinary tract. Increasing body of evidence suggest that MetS and its individual components predispose not only to the development of malignant tumors notably carcinoma of kidney, prostate, ureter or urinary bladder but also to the development of other urological diseases, such as urolithiasis, benign prostate hypertrophy, male hypogonadism or erectile dysfunction. Some patophysiological...
Role of genetic testing at the deciding about the treatment of the kidney tumorsFrom the boundary of urology
MUDr. Robert Novák, MUDr. Jana Katolická, Ph.D.
Urol. praxi. 2025;26(1):40-45 | DOI: 10.36290/uro.2025.023
Renal cell carcinoma (RCC) is a histologically diverse disease, with variable and often unpredictable clinical behavior. Gene expression profiling is a promising technique for refining the diagnosis and staging of RCC, as well as for highlighting potential therapeutic targets (1).
Hematuria - differential diagnosisAt a glance
MUDr. Eva Myslivečková, prof. MUDr. Ivan Rychlík, CSc., FASN, FERA
Urol. praxi. 2025;26(1):35-38 | DOI: 10.36290/uro.2025.022
Hematuria is a symptom of kidney and urinary tract disease. It is important to prove the presence of hematuria and at the same time assess its intensity and origin. Hematuria is classified by quantity into macroscopic and microscopic, and by origin into glomerular (in primary and secondary glomerulonephritis) and non-glomerular (in diseases affecting the kidney parenchyma other than glomeruli, postrenal or extrarenal causes). Diseases causing hematuria also include serious or rapidly progressing conditions that require prompt diagnosis assessment and intervention, either by a urologist or a nephrologist. Therefore, the correct differential diagnosis...
Role of beetroot prior to ordering repeat prostate biopsyGood advice from practice
MUDr. Šárka Kudláčková, Ph.D.
Urol. praxi. 2025;26(1):33-34 | DOI: 10.36290/uro.2025.021
In patients with chronic abacterial prostatitis and elevated PSA, beetroot aids in the treatment of inflammation, thus reducing the PSA level. In addition to relieving patients from the symptoms of chronic prostatitis, the decrease in PSA that is associated with reduction of inflammation may ultimately render prostate rebiopsy unnecessary in the patient.
Disorders of ejaculation in urological diseasesSexual and reproductive medicine in practice
MUDr. Marcela Fontana, Ph.D., FEBU
Urol. praxi. 2025;26(1):28-31 | DOI: 10.36290/uro.2025.020
Difficulties with ejaculation are particularly common among urological patients and often lead to deterioration in quality of sexual life and partnership. Yet are often not disussed. Unfortunatelly, not always are influenceable. Patients should be properly informed about possible negative effects of urological medication or surgical procedures on ejaculation. The following text focuses on anejaculation, retrograde ejaculation, delayed ejaculation and painful ejaculation.
Vitamin D and its impact on sexual and reproductive healthSexual and reproductive medicine in practice
MUDr. Pavel Turčan, Ph.D., FECSM, MUDr. Peter Kepič, MUDr. Jozef Hambálek, MUDr. Pavla Entnerová
Urol. praxi. 2025;26(1):23-27 | DOI: 10.36290/uro.2025.019
Vitamin D plays a very significant role in human health. Its deficiency is associated with many health complications. However, its influence on reproduction and sexual function in both men and women is generally less known. This article provides an overview of this issue and informs about the possibilities of vitamin D supplementation. Vitamin D supplementation is beneficial for health and quality of life in almost all areas. The most effective treatment is with prescription drugs. A new treatment option with calcifediol is an even more effective and safer choice.
Oncological aspects of urolithiasisReview articles
doc. MUDr. Jozef Marenčák, PhD.
Urol. praxi. 2025;26(1):17-22 | DOI: 10.36290/uro.2025.018
Urolithiasis is a complex multifactorial disease resulting from interactions between genetic and environmental factors as well as multiple disease states. The debate about whether urinary calculi induce subsequent malignant changes has continued without a consistent conclusion for several decades. Earlier diagnosis of urolithiasis and its appropriate management can prevent/provide a longer time period for the stones to cause chronic irritation of the local environment or for potentially harmful substances dissolved in the urine to apply their carcinogenic effect. The article clearly deals with current knowledge, opinions and hypotheses in the issue...
The importance of mesh implants in pelvic floor reconstructions in womenReview articles
MUDr. Miroslav Krhovský
Urol. praxi. 2025;26(1):12-16 | DOI: 10.36290/uro.2025.017
Pelvic floor disorders in women are a very common issue. It is estimated that up to 11% of women are experiencing some form of pelvic organ prolapse (POP). It can hardly be assumed that this statistic will change significantly. Operating technologies are still evolving. Separate colporrhaphys performed in the past are no longer relevant and colpocleisis are indicated rarely. A high rate of unsatisfactory outcomes following conventional surgeries has driven the search for new surgical technologies in this area. Reoperation rates are notably high in countries where relevant clinical trials are ongoing. Olsen et al. report a 29.2% incidence of recurrences,...
Comparision of antimuscarinics and beta-3-mimetics in overactive bladder pharmacotherapyReview articles
MUDr. Lenka Plincelnerová
Urol. praxi. 2025;26(1):7-11 | DOI: 10.36290/uro.2025.016
Overactive bladder is a syndrome that leads many patients to visit a urological specialist. Due to its high prevalence in both males and females of any ages, urologist should be well informed about the diagnosis and its treatment. Nowadays, in addition to recommendations of European Association of Urology Guidelines, the treatment tends to be highly individualized. Beside conservative treatment, such as lifestyle changes, pharmacotherapy represents a crucial treatment option. Antimuscarinics are considered a traditional pharmacological choice. Nevertheless, beta-3-mimetics have been successfully used as a combination therapy or even an effective replacement...
Pacienti s LUTS v centru zájmu aneb Co zaznělo na satelitním sympoziu v rámci 70. výroční konference ČUS v Brně a měli byste to vědětHeard at a congress
MUDr. Pavel Tolinger
Urol. praxi. 2024;25(4):238-242 | DOI: 10.36290/uro.2024.080
Laudatio k významnému životnímu jubileu primáře opavské urologie MUDr. Pavla VágneraLaudatio
MUDr. Roman Staněk
Urol. praxi. 2024;25(4):237
Syndrom vyhoření: změna paradigmatuEditorial
Mgr. et Mgr. Marek Vácha, Ph.D.
Urol. praxi. 2024;25(4):175
Retroperitoneal leiomyosarcomaCase report
MUDr. Hana Dittrichová, MUDr. Pavel Hanek, MUDr. Klára Havlová
Urol. praxi. 2024;25(4):233-236 | DOI: 10.36290/uro.2024.079
We describe a case report of a 69-year-old male with suspicious 30 mm mass in the area of left adrenal gland detected on ultrasound examination. Based on imaging examinations it was not possible to rule out a malignant potential of the lesion. The patient underwent left side adrenalectomy, the histological examination revealed a moderately differentiated, well-circumscribed leiomyosarcom. The adrenal gland was without infiltration. There were no signs of metastatic disease. According to the recommendation of multidisciplinary oncology team, he is placed under surveillance. The patient underwent a follow-up restaging CT 6 months after the surgery with...
Renal cell carcinoma metastasis to the breastCase report
MUDr. Paulína Kubalcová, MUDr. Elena Loumová, MUDr. Michaela Uhrinová Vukušičová
Urol. praxi. 2024;25(4):229-232 | DOI: 10.36290/uro.2024.078
While breast cancer represents the most common form of malignancy in women, breast metastases associated with extramammary malignancies are very rare. Metastatic breast tumors account for less than 1 % of all breast malignancies, with the majority originating in the contralateral breast. Although the renal cell carcinoma is the most common form of cancer of the urogenital tract, only a few cases of breast metastases have been described. We present a case report of a woman with synchronous metastasis in the breast in 2016. 6 years after nephrectomy was developed metachronic metastasis in the same breast. The patient is free of metastases apart from...
Endovascular superselective embolization in the therapy of traumatic high-flow priapismCase report
MUDr. Quynh Anh Demjanenko, MUDr. Jan Porod, MUDr. Samuel Heller, Ph.D., MUDr. Pavel Hanek, MUDr. Klára Havlová
Urol. praxi. 2024;25(4):225-228 | DOI: 10.36290/uro.2024.077
Authors present a case report of patient with post-traumatic high-flow (arterial) priapism and the subsequent therapeutic approach consisting of endovascular superselective embolization of bilateral pseudoaneurysm of cavernosal bodies, which lead to preservation of erection function in almost full extent.
Phimosis in childrenAt a glance
doc. MUDr. Oldřich Šmakal, Ph.D.
Urol. praxi. 2024;25(4):222-224 | DOI: 10.36290/uro.2024.076
Phimosis, a condition in which the foreskin is too tight to be retracted over the glans, is a frequent reason for a child's visit to the doctor. Its treatment depends on the correct diagnosis and patient complaints. In primary, or congenital phimosis, the approach is as conservative as possible; in acquired, or secondary, phimosis, most cases require a circumcision to be performed. The mainstay of conservative treatment is proper care of the boy's penis allowing a spontaneous development of the foreskin that can be promoted by local administration of a corticoid ointment. When circumcision is indicated, its extent will be determined by the intraoperative...
Male infertility and posibilities of pharmacological therapySexual and reproductive medicine in practice
MUDr. Dalibor Jozef Fedák
Urol. praxi. 2024;25(4):218-221 | DOI: 10.36290/uro.2024.075
Historically rather ignored male infertility is alone or in combination the cause of approximately 60% infertile couples. Inability of couple to conceive leads to psychosocial stress. Role of systematic diagnostics and treatment of male infertility is to understand the cause, improve spermatogenesis and increase chances of successful fertilization.
Clinical application of liquid biopsy in uro-oncologyFrom the boundary of urology
MUDr. Aneta Rozsypalová
Urol. praxi. 2024;25(4):213-217 | DOI: 10.36290/uro.2024.074
The liquid biopsy is a new promising option in diagnosis, monitoring during the treatment and early detection of relapse. A big advantage of liquid biopsy is its mini-invasivity, the possibility of frequent repetition and thus real-time monitoring of the disease. This article summarizes the current results of liquid biopsy in urological malignancies.
Ambulatory parenteral antibiotic therapy in urology: innovations and perspectivesFrom the boundary of urology
MUDr. Marek Štefan, MBA
Urol. praxi. 2024;25(4):210-212 | DOI: 10.36290/uro.2024.073
The review article addresses the issues of outpatient parenteral antibiotic therapy (OPAT) in urology. OPAT is a treatment modality that allows intravenous administration of antibiotics in an outpatient setting. Urology is one of the fields where OPAT can be utilized, most commonly to treat urinary tract infections caused by multidrug-resistant bacteria (e. g., ESBL-producing strains) in patients whose health condition does not require hospitalization. OPAT can be implemented in several ways: administering long-acting antibiotics (ceftriaxone, ertapenem, gentamicin, and amikacin) once daily at the clinic or the application of various antibiotics continuously...
Multidisciplinary approach in the diagnosis and therapy of renal tumoursFrom the boundary of urology
MUDr. Jindřich Kopecký, Ph.D., MUDr. Jiří Špaček, MUDr. Petr Hoffmann, Ph.D., MUDr. Miroslav Podhola, Ph.D., MUDr. Peter Priester, MUDr. Alžbeta Hlodáková
Urol. praxi. 2024;25(4):205-209 | DOI: 10.36290/uro.2024.072
This review article provides a comprehensive view of diagnostics of renal tumours from perspective of different disciplines involved in the diagnosis and treatment of renal tumours (urologists, clinical oncologists, radiologists and pathologists). Diagnostic strategies, treatment options, and the importance of a multidisciplinary team to optimize treatment outcomes for patients with renal tumors outside the renal pelvis are discussed.
Urological care of a spinal patient from the perspective of a rehabilitation doctor Urologist as part of multidisciplinary teamFrom the boundary of urology
MUDr. Hana Davidová
Urol. praxi. 2024;25(4):198-203 | DOI: 10.36290/uro.2024.071
Spinal cord injury is one of the most serious disabilities interfering with a number of the body's physiological systems. The management of spinal patients is challenging, requiring a multidisciplinary approach and specialized care. For this reason, a spinal programme has been established in the Czech Republic for more than 20 years. Proper urological care is important immediately after the injury. During the stay at spinal rehabilitation units, it is tailored to the particular individual. It is always based on a thorough urological evaluation as well as functional and cognitive abilities of the patient. Collaboration between the rehabilitation team...
Paliative care in urologyReview articles
MUDr. Milan Král, Ph.D.
Urol. praxi. 2024;25(4):194-197 | DOI: 10.36290/uro.2024.070
Palliative care is now a fully recognized part of complex medicine and offers a completely irreplaceable approach to the care of not only oncological patients. It includes a set of treatment procedures that do not aim to cure the given diagnosis, but to ensure the patient with an incurable disease, in the pre-terminal or terminal phase of life, maximum comfort, taking into account his physical and psychological problems. The urologist deals not only with primarily urological diagnosis, but also helps with the diagnosis and treatment of urological complications of primarily other diseases. The presented article aims to point out the role of the urologist...
Diabetes mellitus from the point of view of a urologistReview articles
doc. MUDr. Jozef Marenčák, PhD.
Urol. praxi. 2024;25(4):185-193 | DOI: 10.36290/uro.2024.069
Diabetes mellitus (DM) is a global epidemic characterized by elevated blood glucose levels with significant morbidity and mortality. DM can lead to acute and chronic complications in virtually all body organs, including the urogenital system. The issue of diagnosis and treatment of diabetic patients with urological and andrological problems is complex, extremly serious and constantly evolving. The article deals with the most common urological conditions that are specific to DM. Urological complications can last an unrecognizably long time, often oligosymptomatically, but they are often life-threatening for patients. The proper tretment of these diseases...
New approaches in the treatment of testicular cancerReview articles
MUDr. Pavel Navrátil, FEBU, MUDr. Minh Nguyet Tranová, MUDr. Jiří Špaček, FEBU, MUDr. Michal Balík, Ph.D., doc. MUDr. Jaroslav Pacovský, Ph.D.
Urol. praxi. 2024;25(4):180-184 | DOI: 10.36290/uro.2024.068
Testicular germ cell tumors represent a significant challenge in the field of oncology, despite their relatively low incidence. This article focuses on current approaches in their treatment, emphasizing the optimization of care and minimizing the risk of relapse and treatment toxicity. Standard procedures such as orchiectomy, chemotherapy, radiotherapy, and lymphadenectomy are discussed. Special attention is given to the role of new biomarkers, such as miR-371a-3p, which improve the accuracy of diagnosis and treatment monitoring. The article also reflects current trends in therapy de-escalation and research of new targeted therapeutic approaches, including...
Vzpomínka na doc. MUDr. Richarda Reifa, CSc.Memory
doc. MUDr. Jan Báňa, CSc.
Urol. praxi. 2024;25(3):170
Proč mizí z medicíny laskavost?Editorial
MUDr. Radkin Honzák, CSc.
Urol. praxi. 2024;25(3):103
Metastasis of renal cell carcinoma into prostateCase report
MUDr. Silvia Klebanová, MUDr. Martin Sutorý, CSc.
Urol. praxi. 2024;25(3):168-169 | DOI: 10.36290/uro.2024.064
We present a case report of patient with localised clear renal cell carcinoma who underwent left side radical nephrectomy. Nine years later, a metastasis of renal cell carcinoma to the prostate was detected, and subsequently metastatic process to the lungs was verified.
Urinary tract endometriosisCase report
MUDr. Michal Buchta, MUDr. Oldřich Matys, MUDr. Martin Němec
Urol. praxi. 2024;25(3):162-166 | DOI: 10.36290/uro.2024.063
The authors present two case reports of patients with endometriosis of the bladder and ureter who underwent examination and operative treatment at the given department. The case reports describe possible diagnostic uncertainity and the necessity of complex interdisciplinary approach, especially in advanced disease. In this article, the authors further describe the issue of endometriosis of the urinary tract as a diagnostic unit that a urologist may encounter in his practice.
Radical removal of a rare retroperitoneal sarcoma in a young manCase report
MUDr. Petra Koňaříková, MUDr. Miroslav Louda, Ph.D., MBA, MUDr. Jiří Špaček, MUDr. Lukáš Krbal, Ph.D., prof. MUDr. Miloš Broďák, Ph.D.
Urol. praxi. 2024;25(3):160-161 | DOI: 10.36290/uro.2024.062
We present a case report of radical removal of a retroperitoneal sarcoma in a young man. It was a rare histological type of tumor, sclerosing epithelioid fibrosarcoma. It occurs at younger age and is associated with higher aggressiveness than similar tumors. Not only the complete removal of the tumor, but also a radical resection of the entire ileocecal segment was performed. This proved to be very prescient and complete resection was achieved without a positive surgical margin.
DyspareuniaSexual and reproductive medicine in practice
MUDr. Marek Broul, Ph.D., MBA, FECSM, MUDr. Petra Kučerová, MUDr. Kamila Žižková, Mgr. Aneta Hujová
Urol. praxi. 2024;25(3):156-159 | DOI: 10.36290/uro.2024.061
Dyspareunia is defined as painful sexual intercourse. It can have a significant impact on partner relationships and the overall quality of life of affected women. This article reviews the current knowledge regarding the definition, prevalence, diagnosis and treatment of dyspareunia. It summarizes key information on current knowledge about dyspareunia and provides an essential foundation for clinical practice in sexual health.