Moderní paliativní medicína

MUDr. Irena Závadová

Urol. praxi. 2019;20(4):147  

Androgen deprivation therapy of prostate cancer and cardiovascular morbidity

MUDr. Otakar Čapoun, Ph.D., FEBU

Urol. praxi. 2019;20(4):150-156 | DOI: 10.36290/uro.2019.068  

Androgen deprivation therapy (ADT) of prostate cancer (PC) is burdened by a number of adverse events or effects (AEs). Immediate AEs are hot flashes and sweating, the main AE of long-term ADT include body feminisation, sexual and cognitive changes, fatigue or sleep disturbances. Other AEs are related to metabolic changes (osteoporosis, changes in lipid metabolism, insulin resistance and metabolic syndrome). Serious AEs include fractures and cardiovascular events (CVEs). Treatment with agonists of luteinizing hormone-releasing hormone (LHRH) is associated with a higher risk of CVEs compared to the LHRH antagonist degarelix. Higher rate of CVEs during...

BCG – history, method principe, indication, effectivity, dosage

MUDr. Petr Hušek, FEBU, MUDr. Jaroslav Pacovský, Ph.D., prof. MUDr. Miloš Broďák, Ph.D.

Urol. praxi. 2019;20(4):157-160 | DOI: 10.36290/uro.2019.069  

Bacillus Calmette –Guerine intravesical therapy has become a standard treatment of high grade non-muscle invasive blader cancer(Ta, T1) and cancer in situ (CIS) in clinical praktice with acceptable results. A lot of questions are still unclear. Goal of an article isthe summary BGG treatment and description of interesting historical evolution.

Benign prostatic hyperplasia – latest pharmacotherapy options, risks and limitations of treatment

MUDr. Barbora Žemličková, MUDr. Marcela Čechová

Urol. praxi. 2019;20(4):161-165 | DOI: 10.36290/uro.2019.070  

Benign prostatic hyperplasia (BPH) presents one of the most frequent condition among middle-aged and elderly men. Even thoughits benign biological potential, symptoms of BPH can have negative impact on patient’s quality of life and cause chronic or acutecomplications. Properly chosen pharmacotherapy represents an effective way to reduce patient’s complaints and minimize therisk of complications or need of surgical intervention.

Medical marijuana as a medicament for chronic pelvic pain?

doc. MUDr. Jozef Marenčák, PhD.

Urol. praxi. 2019;20(4):166-170 | DOI: 10.36290/uro.2019.071  

Marijuana is a mixture of dry parts of leaves, fruits and flowers of female plants of the genus Cannabis with declared cannabinoid content. Cannabinoids is the collective term for a group of chemical compounds that either are derived from Cannabis plant, or are synthetic analogues, or occur endogenously. Although cannabinoids act mostly at the level of currently known cannabinoid receptors, they may have cross-reactivity and also act, for example, at opioid receptors. Unfortunately, there are so far only rare clinical studies to support cannabis use in patients with chronic pelvic pain syndrome (CPPS). The article reviews current knowledge about the...

Current options of treating vulvovaginal discomfort

doc. MUDr. Tomáš Fait, Ph.D.

Urol. praxi. 2019;20(4):171-174  

Vulvovaginal discomfort is a common complaint in gynaecological patients. More frequently, the cause is dysbacteriosis ratherthan infection. The condition tends to recur. In addition to anti-infective therapy, restoration of the vaginal milieu with probioticsis recommended for both treatment and prevention.

Urodynamic examination – indication, performance, interpretation

MUDr. Roman Sobotka, FEBU, prof. MUDr. Tomáš Hanuš, DrSc.

Urol. praxi. 2019;20(4):175-182  

The article briefly summarizes the neurological regulation of the lower urinary tract and breaks down possible dysfunctions relatedto nervous system damage. Furthermore, the article deals with the indication and performance of urodynamic examinationincluding noninvasive urodynamics. It also analyzes and explains individual methods of urodynamic examination.

Bladder cancer in young adult

MUDr. Peter Kepič

Urol. praxi. 2019;20(4):183-185 | DOI: 10.36290/uro.2019.074  

Bladder cancer is one of the most common forms of malignancies involoving the urinary system. Multiple risk factors have been associated with its etiology. The most common are tobacco smoking and chemical exposures most often from the working environment. It is usually diagnosed in older people with an average age around 70 years. In rare cases, bladder cancer can be diagnosed in the pediatric population and in young adults, where it usually presents as a low-grade, non-invasive disease. In our case, we discussed the 28-year-old man who was at our hospital due to acute pancreatitis. As an accidental founding on CT scan of abdomen we described a papillary...

Recurrent urinary tract infections and cystinuria

MUDr. Zuzana Vyoralová, MUDr. Tomáš Šálek, Ph.D.

Urol. praxi. 2019;20(4):186-190 | DOI: 10.36290/uro.2019.075  

We present a case of a 14-year-old female patient with cystine lithiasis. At the age of 8 months she had her first febrile urinary infection. Furthermore, she had no clinical signs of infection, but pyuria and significant bacteriuria were repeatedly detected. She was treated with antibiotics for these findings. In the absence of clinical difficulties parents refused further investigation of the patient. The diagnosis was made at the age of 12 by cystine crystals in the urine sediment, followed by evidence of cystinuria with nephrolithiasis. After the surgical intervention, dietary and medical treatment continues, with the patient free from pyuria and...

Education of patiens after kidney transplantation

Mgr. Pavla Kordulová, Bc. Adéla Rebcová

Urol. praxi. 2019;20(4):191-194 | DOI: 10.36290/uro.2019.076  

Renal transplantation is a method of choice for irreversible renal failure and has become a routine part of treatment through advances in surgical techniques and immunosuppressive therapy options. In order for the treatment process to be successful, patients must be properly instructed about the treatment regime at home. The aim is to improve the postoperative quality of treatment of patients, but also to support the long-term function of the transplanted kidney.

(URO)logické kroky ke zdraví 2019

MUDr. Michaela Matoušková

Urol. praxi. 2019;20(4):196  

Informace o proběhlém 7. ročníku Video-semináře: Typy a triky v urologické operativě

prof. MUDr. Miloš Broďák, Ph.D.

Urol. praxi. 2019;20(4):197-198  

MUDr. Antonín Leder (27. 7. 1940–1. 8. 2019)

Urol. praxi. 2019;20(4):198