Jaro je tady i se svými riziky

MUDr. Radkin Honzák, CSc.

Urol. praxi. 2025;26(2):63

Personalized pharmacotherapy for mLUTS - an effective approach to manage OAB symptoms, preserving sexual function and improving quality of life

MUDr. Marcela Fontana, Ph.D., FEBU

Urol. praxi. 2025;26(2):65-69 | DOI: 10.36290/uro.2025.038

Pharmacotherapy is an effective treatment for most men with lower urinary tract symptoms (mLUTS). The goal of treatment is to improve symptoms and, especially, to improve the quality of life. Most men prefer treatment with the least risk of side effects, which effectively affects mainly overactive bladder symptoms and preserves sexual functions. There is increasing emphasis on personalized medicine and tailoring treatment as much as possible to the specific needs and preferences of the patient. Optimal therapeutic effect is often achieved through combinations of medications from multiple drug groups.

Long-term consequences of radical prostatectomy: How to improve patients' quality of life

MUDr. Hanka Princlová, MUDr. Pavel Navrátil, Ph.D., FEBU

Urol. praxi. 2025;26(2):70-73 | DOI: 10.36290/uro.2025.039

Robot-assisted radical prostatectomy is the standard treatment for localized prostate cancer. However, late functional complications such as stress urinary incontinence, erectile dysfunction, and bladder neck strictures continue to be critical factors affecting patients' quality of life. This article explores strategies to prevent these complications through optimized surgical techniques and individualized rehabilitation care. Emphasis is placed on minimally invasive surgical approaches, preservation of key anatomical structures, and comprehensive postoperative management, including physiotherapy, pharmacological support, and technical aids. Studies...

Psychosocial aspects of active surveillance for prostate cancer

doc. MUDr. Otakar Čapoun, Ph.D., FEBU

Urol. praxi. 2025;26(2):74-78 | DOI: 10.36290/uro.2025.040

For selected patients with low-risk prostate cancer (PC), active surveillance (AS) represents the method of choice aimed at delaying or avoiding radical treatment. However, AS can cause anxiety and uncertainty. Patients also often receive insufficient, confusing, and difficult-to-understand information, leading to anxiety and stress. Psychosocial support and interventions focused on lifestyle improvement can play a key role in managing uncertainty and enhancing patients' confidence in AS. Patient and family education is essential, as it also reduces stress and improves cooperation. Patient support groups and psychotherapeutic interventions may be beneficial...

Emerging trends in telemedicine and artificial intelligence in urology

MUDr. Martin Malý, MUDr. Alžběta Kantorová, doc. MUDr. David Zogala, Ph.D., doc. MUDr. Otakar Čapoun, Ph.D., FEBU, prof. MUDr. Viktor Soukup, Ph.D., FEBU, MHA

Urol. praxi. 2025;26(2):79-86 | DOI: 10.36290/uro.2025.041

This article explores the emerging trends and technologies in urology, focusing on telemedicine and artificial intelligence. It provides a brief overview of the benefits of telemedicine and its impact on the patient-physician interactions. The article subsequently explores in detail the use of artificial intelligence, which is currently gaining considerable interest from both general public and medical professionals. Its potential in urology has been tested in a number of clinical studies, particularly in the field of uro-oncology and, to a lesser extent, in benign urological diseases. The aim of this article is to identify the key advances in this...

The Balint group as a possibility for doctor's stress reduction and burnout prevention

MUDr. Jiří Poněšický, FEBU, FECSM

Urol. praxi. 2025;26(2):87-90 | DOI: 10.36290/uro.2025.042

The article addresses stress and burnout syndrome in general, the results of research on burnout syndrome among Czech doctors, and approaches to coping with these challenges. It specifically focuses on explaining the functioning of Balint groups as a form of psychological hygiene for doctors and as a mens leading to a better understanding of the doctor-patient relationship.

Premature ejaculation

MUDr. Marek Broul, Ph.D., MBA, FECSM, Mgr. Aneta Hujová

Urol. praxi. 2025;26(2):91-95 | DOI: 10.36290/uro.2025.043

The authors summarize the problem of premature ejaculation and modern treatment options.

Prostate cancer - interaction potential of used drugs

PharmDr. Roman Goněc, PharmDr. Vojtěch Ondra, doc. PharmDr. Jan Juřica, Ph.D.

Urol. praxi. 2025;26(2):102-107 | DOI: 10.36290/uro.2025.046

Advances in the treatment of prostate cancer in the last years have made it possible to cnsider prostate cancer a chronic disease, particulary in older patients. These patients are usually polymorbid and with increasing number of drugs they use, the risk of interactions also rises. Such interactions could lead to increased toxicity or reduced effect of anti-cancer drugs. However, mainly enzalutamide and apalatumide can significantly reduce the effectiveness of many commonly used drugs, and it is essential that the physicians are well-informed about these risks. In Czech Republic, enzalutamide, apalutamide, darolutamide, abiraterone, talazoparib, olaparib,...

Benign prostatic hyperplasia - short summary of the current knowledge and practical guidelines on benign prostatic hyperplasia

MUDr. Kamil Belej, Ph.D., FEBU, MBA

Urol. praxi. 2025;26(2):96-98 | DOI: 10.36290/uro.2025.044

Short summary of the current knowledge and practical guidelines on benign prostatic hyperplasia.

Complicated percutaneous nephrolithotomy in a kidney transplant patient

MUDr. Minh Nguyet Tranová, MUDr. Pavel Navrátil, Ph.D., FEBU

Urol. praxi. 2025;26(2):108-110 | DOI: 10.36290/uro.2025.047

In patients with a transplanted kidney, percutaneous nephrolithotomy (PCNL) is a procedure that requires consideration of the graft´s specific anatomical and physiological conditions. This case report describes a 69-year-old man who underwent PCNL due to recurrent graft infections and the progression of stone size. The procedure was successfully completed without residual lithiasis; however, postoperative complications, including bleeding and infection, required emergency surgical revision and intensive care. Prompt intervention and subsequent treatment preserved the function of the transplanted kidney. This case highlights the importance of precise...

Intravesical instillation therapy with hyaluronic acid in recurrent urinary tract infections

MUDr. Marcela Fontana, Ph.D., FEBU

Urol. praxi. 2025;26(2):99-101 | DOI: 10.36290/uro.2025.045

Recurrent urinary tract infections are very common in clinical practice. Endovesical installation of hyaluronic acid helps to restore the protective glycosaminoglycan layer on the surface of bladder urothelium and reduces the frequency of recidives. This treatment represents an effective option especially for patients in whom regime measures in combination with non-antimicrobial or antimicrobial prophylaxis has been unsuccessful.