Zůstane pohlavní styk i nadále preferovaným způsobem lidské reprodukce?

doc. MUDr. Jaroslav Zvěřina, CSc.

Urol. praxi. 2018;19(4):155  

The issue of sterile pyuria in urological practice

MUDr. Jiří Kladenský

Urol. praxi. 2018;19(4):158-161 | DOI: 10.36290/uro.2018.078  

Pyuria (leukocyturia) is a typical sign of urinary tract infections and is usually accompanied by bacteriuria in the urinesediment. In sterile (abacterial) pyuria, there is no finding of bacteriuria in the urine sediment and the urine culture isnegative. As a matter of fact, sterile pyuria is not rare and occurs in the population in 14 % of women and 3 % of men. Thearticle deals with the most frequent causes of sterile pyuria and briefly presents the basic diagnostic options within thedifferential diagnosis.

Current surgical treatment options of pelvic organ prolapse

MUDr. Miroslav Krhovský

Urol. praxi. 2018;19(4):162-167 | DOI: 10.36290/uro.2018.079  

The last 25 years witnessed great changes in the reconstructive surgical procedures on the female pelvic floor. This development hadpredominantly been spurred on by an increasing number of relapses after traditional surgery had been performed. Positive results thatwere accomplished while using the mesh in laparoscopic hernia and stress incontinence surgeries also built a foundation for implantingthe mesh in pelvic organ prolapse (POP) surgery. As a result, this technology has today been used routinely in correcting the POPs. Afterit was introduced, the amount of anatomical relapse cases has decreased although it cannot be asserted with full confidence...

Treatment of metastatic clear-cell renal cell carcinoma – cabozantinib – experience and inclusion
in treatment algorithm

MUDr. Jana Katolická, Ph.D., MUDr. Sabina Svobodová, MUDr. Jiří Vaníček, Ph.D., Mgr. Pavlína Prosecká, MUDr. Petr Filipenský, Ph.D.

Urol. praxi. 2018;19(4):168-171 | DOI: 10.36290/uro.2018.080  

Renal cell carcinoma, even in the metastatic setting, can be treatable, thus extending patient survival significantly. Cabozantinibadministered after failure of treatment with tyrosine kinase inhibitors substantially prolonged the overall survival, delayed diseaseprogression, and improved the rate of objective responses in patients with advanced clear-cell renal cell carcinoma whohad received antiangiogenic therapy. Patients treated with it can maintain a good quality of life with an acceptable safety profile.

Role of tumor markers in testicular cancer

MUDr. Aneta Rozsypalová

Urol. praxi. 2018;19(4):172-175 | DOI: 10.36290/uro.2018.081  

Serum tumor markers (onkomarkers) play critical role in diagnosis, staging, risk stratification and prognosis of patients with testicular tumors.They are usefull as an important index to monitor during the therapy and than aids in the early detection of disease recurrence. Commontesticular cancer tumor markers are α-fetoprotein (AFP), human chorionic gonadotrophin (hCG), lactate dehydrogenase (LDH). The limitationof these markers is sensitivity and specificity. There are many others conditions that can cause elevation of these markers. Because ofthat new markers are finding, the biggest potential have studies based on detection of non-coding RNAs...

Diagnosis and treatment of penile cancer

MUDr. Michael Pešl, FEBU

Urol. praxi. 2018;19(4):176-180 | DOI: 10.36290/uro.2018.082  

Penile cancer is a disease with a very low incidence in the Czech Republic. For this reason it is advisable that patients withthis diagnosis be referred to and managed in centres where the staff has experience with this disease. This centralizationof care leads to better oncological outcomes. The paper presents the latest update of the TNM classification and the newhistopathological classification of premalignant lesions, which facilitates and refines the indications to surgical treatment.The authors provide an overview of the options of surgical treatment both in terms of treatment of the primary tumour andin terms of management of nodal involvement....

Multiple sclerosis and male infertility

doc. MUDr. Jozef Marenčák, PhD.

Urol. praxi. 2018;19(4):181-184 | DOI: 10.36290/uro.2018.083  

Multiple sclerosis (MS) is a demyelinating disease of unknown etiology that affects the central nervous system – both the brain andthe spinal cord. Male fertility can be compromised in the neurological patient by erectile dysfunction (ED), ejaculation disorder,impaired sperm quality or various combinations of these three disorders. ED can be managed by an increasingly invasive rangeof treatments including medications, injection therapy and the surgical insertion of a penile implant. Retrograde ejaculation ismanaged by medications to reverse the condition in mild cases and in bladder harvest of semen after ejaculation in more severecases. Anejaculation...

Urological medication in pregnancy and lactation

MUDr. Jakub Pavelka, MUDr. Roman Staněk

Urol. praxi. 2018;19(4):185-187  

A short summary of the most common urological medication prescribed to patients during pregnancy and lactation. Both conditions,despite being natural in the life of a woman, cause troublesome deciding to several doctors. This is due to possible side effectsnot only affecting the mother, but also due to possible teratogenous effects on the foetus and transfer to child per breast milk.

Non-differentiated retroperitoneal sarcoma

MUDr. David Čapka, MUDr. Věra Mašková, MUDr. Ivan Kolombo, FEBU, MUDr. Petr Klézl, MBA, MUDr. Petr Nencka, FEBU, MUDr. Josef Šach, doc. MUDr. Robert Grill, Ph.D., MHA

Urol. praxi. 2018;19(4):188-191 | DOI: 10.36290/uro.2018.085  

We describe the case of a patient with undifferentiated kidney sarcoma that spreads to retroperitoneum. It was diagnosed basedon imaging methods, histological and molecular biopsy examination. The patient was indicated primary for chemotherapy duringwhich the disease progressed further and the patient was subsequently indicated for palliative treatment.

Laparoscopic pyeloplasty in an 82 year old female patient with a pelvis duplex

MUDr. David Čapka, MUDr. Petr Nencka, FEBU, MUDr. Petr Klézl, MBA, MUDr. Ivan Kolombo, FEBU, doc. MUDr. Robert Grill, Ph.D., MHA

Urol. praxi. 2018;19(4):192-194  

We describe the case of a patient with hydronephrosis of the right kidney with anomal pelvis duplex in which laparoscopic pyeloplastywas indicated. We present the results of the examination before the indication for operation, the procedure itself andthe post-operation follow-up screening.

Leiomyosarcoma of the inferior vena cava – per surgery finding

MUDr. Hana Musilová, MUDr. Roman Staněk, MUDr. Gabriela Černá, MUDr. Iva Zambo, Ph.D., MUDr. Jiří Hájek

Urol. praxi. 2018;19(4):195-197 | DOI: 10.36290/uro.2018.086  

Herein we present a case report of a 46 year – old female patient diagnosed with tumor of right kidney. Pacient underwent laparoscopicnephrectomy. Final histology report determinated suprising result – primary leiomyosarcoma of the inferior vena cava.Between years 1961–2008 were reported 1 210 tumors of the inferior vena cava. 85 cases were diagnosed as primary leiomyosarcoma.

(Uro)logické kroky ke zdraví – Praha 28. 9. 2018

MUDr. Michaela Matoušková

Urol. praxi. 2018;19(4):203  

Vzpomínka na pana profesora MUDr. Jana Kučeru, DrSc., u příležitosti jeho nedožitých 100. narozenin (nar. 7. 11. 1918)

doc. MUDr. Jan Báňa, CSc., doc. MUDr. Richard Reif, CSc., prof. MUDr. Vladimír Študent, Ph.D.

Urol. praxi. 2018;19(4):201-202