Urol. praxi. 2019;20(3):129-132 | DOI: 10.36290/uro.2019.062

Genetic impact on spermatogenesis

prof. MUDr. Pavel Trávník, DrSc.
REPROMEDA Biology Park, Brno
Institut postgraduálního vzdělávání ve zdravotnictví, Praha

The cause of male infertility is frequently genetic. The genetic cause may be the chromosome abnormality or the mutation of a gene
important for the spermatogenesis or the sperm function. The abnormality could disturb the sperm amount, their morphology,
motility or the ability to penetrate the oocyte envelopes, fuse with the oocyte and activate them. Genetic error can also stop the
early embryo development. The error affecting male fertility is possibly connected with the occurrence of congenital defects in
descendants and therefore genetic examination of the man with fertility disturbance is important.

Keywords: sperm, infertility, genetic cause

Published: July 1, 2019  Show citation

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Trávník P. Genetic impact on spermatogenesis. Urol. praxi. 2019;20(3):129-132. doi: 10.36290/uro.2019.062.
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