Urol. praxi, 2015; 16(4): 165-168

Malignant melanoma of the urethra

MUDr.Roman Šamudovský, MUDr.Jaroslav Všetička, Ph.D.

Urologické oddělení, Nemocnice Jablonec nad Nisou, p. o.

69 year old patient , in the meantime without positive urological history, examination for asymptomatic hematuria at the urology clinic.

On the basis of clinical, laboratory, and imaging was performed with flexible cystoscopy. In this investigation, we found urethral polyp,

accompanied by urethral stenosis, because the patient is indicated for the optical urethrotomy and urethral polyp endoresection. The

polyp was later verified histologically and immunohistochemically as malignant melanoma of the urethra. Primary malignant melanoma

of the male urethra is very rare and the prognosis of this disease is poor. Subsequent CT examination of the lungs and abdomen

revealed multiple foci in the lung parenchyma suggestive of metastases . Patient communication after diagnosis treatment at our facility

interrupted, but intermittent hematuria soon came back. Based on the examination revealed melanoma recurrence and progression of

lung findings . Reoperated patient and sent to chemotherapy, but after that it appeared extraurethra relapse. The patient is encouraged

instantaneous total amputation of the penis with perineostomy, the patient refused . Later, however, comes with a request to undergo

the recommended capacity . Due to massive disease progression and after consultation with higher urological center of power is withdrawn

and the patient is sent to a biological therapy , which is currently undergoing.

Keywords: hematuria, urethrae, malignant melanoma, amputation

Published: November 1, 2015  Show citation