Urolog. pro Praxi, 2010; 11(1): 29-31 [Interní Med. 2009; 11(11): 515-517]

Medication of erectile dysfunction and its security

doc.MUDr.Michal Pohanka, Ph.D.¹, prof.MUDr.RNDr.Luboslav Stárka, DrSc.²

¹ Gynekologicko-porodnická klinika FN Brno a Sexuologický ústav 1. LF UK, Praha

² Endokrinologický ústav, Praha

Erectile dysfunction is a relatively frequent disorder substantially increasing with age. The high effective treatment of erectile dysfunction

by drugs based on inhibition of phosphodiesterases type 5 (sildenafil, tadalafil, vardenafil) tempt to prescription of these drugs

without careful examination. It is demanded to include besides personal history and physical examination also laboratory data for exclusion

of diseases associated with erectile dysfunction as diabetes mellitus, hyperprolactinemia or hypogonadismus. Contraindicated

for treatment by inhibitors of phophodiesterases are nitrates. For patients on intensive antihypertension therapy or with severe cardiac

diseases cardiovascular examination is a rule. The physician should made the patient acquainted with side-effects as headaches, flush,

dyspepsia, nasal mucosal congestion, low-back aches, changes in colour vision, and, especially with the rare but still existent possibility

of priapism, which needs an urological intervention.

Keywords: erectile dysfunction, inhibitors of phosphodiesterases, contraindications, side-efects, examination

Published: March 1, 2010  Show citation