Urolog. pro Praxi, 2009; 10(4): 215-217

Primary hormone therapy for localized prostate cancer

MUDr. Vladimíra Stáhalová

Ústav radiační onkologie 1. LF UK a FN na Bulovce, Praha

Hormonal therapy (HT) of prostata carcinoma produces delayed clinical progression in all stages of disease. Locally advanced and

regional stage (T3N0–1M0GX) is domain of neoadjuvant or adjuvant hormonotherapy in combination with radiotherapy (RT). Mortality

reduction of prostata cancer is accomplished by early diagnosis, increasing surgical a radiotherapeutic procedures and introduction

of hormonal therapy into primary treatment (table 1). Recommended proceedings are verified by clinical trials, which combine agressive

treatment primary tumor with hormonal therapy in the same time. It is neccessary to determinate an indivudual risk of each patient

before treatment (table 2). Hormonal therapy in combination with radiation therapy in intermediate and high risk patients is evidence

based. Duration and way of hormonal manipulation are controversial.

Keywords: radiotherapy, neoadjuvant and adjuvant hormonal therapy.

Published: November 1, 2009  Show citation