Co to je za nemoc a proč ji neléčíme?

prof. MUDr. Eva Králíková, CSc.,

Urol. praxi. 2019;20(2)  

Treatment and prevention of recurrent urinary tract infections

MUDr. Miroslava Ryšánková

Urol. praxi. 2019;20(2):54-57 | DOI: 10.36290/uro.2019.049  

Recurrent urinary tract infections are frequent job description urology clinic. The most common are cystitis in women, prostatitisin men. Other common recurrent diseases are pyelonephritis. Treatment of the infection itself is not difficult, but it is necessary totreat it in a targeted manner. A further set of measures is more demanding to prevent recurrent attacks. Combination regimens,natural preparations, immunoprophylaxis or chemoprophylaxis are combined.

The importance of phytopharmaceuticals in treating chronic prostatitis

PharmDr. MVDr. Vilma Vranová, Ph.D.

Urol. praxi. 2019;20(2):58-61 | DOI: 10.36290/uro.2019.050  

Inflammatory diseases of the prostate are the most frequent urological diagnosis in men younger than 50 years, ranking as third in older age groups. An acute inflammation is relatively rare, with chronic inflammations being more common and posing much greater diagnostic and therapeutic challenges, which, as has been shown in many clinical trials, can be significantly influenced by the fact that the causative agents of prostatitis form biofilms. Making biofilm formation difficult or impossible reduces the fighting capacity of the pathogens while facilitating further treatment, e.g. increasing the effect of antimicrobial therapy. A synergistic effect...

The role of ARTAs in treating metastatic castration-resistant prostate cancer

MUDr. PharmDr. Jan Dvořák

Urol. praxi. 2019;20(2):62-65 | DOI: 10.36290/uro.2019.051  

The article deals with the role of ARTAs, particularly in treating metastatic castration-resistant prostate cancer, presenting availabledata and their utilization in practical treatment-related decision making.

Varicocele

MUDr. Marcel Drlík, FEAPU, doc. MUDr. Radim Kočvara, CSc., FEAPU

Urol. praxi. 2019;20(2):66-69 | DOI: 10.36290/uro.2019.009  

Varicocele is defined as an enlarged overfilled pampiniform venous plexus due to venous reflux. It is a very frequent pathology,affecting about 14–20% of adolescents and young men. Although many studies proved an existing link between varicocele andimpaired fertility, only 20% of men with varicocele are subfertile. Selection of a patient who would benfit of a treatment and thebest treatment option still remain matters of debate.

Cryptorchidism in childhood and adulthood

MUDr. Jan Šarapatka, MUDr. Romana Šarapatková, MUDr. Jan Vrána, doc. MUDr. Oldřich Šmakal, Ph.D.

Urol. praxi. 2019;20(2):70-74 | DOI: 10.36290/uro.2019.006  

Cryptorchidism is the most commonly diagnosed developmental birth defect of external genitalia in new born male babies. The incidence of cryptorchidism is estimated to be between 1–3 % of boys born after full-term pregnancies. However, the incidence is much higher in the case of boys born prematurely (15–30 %). Descent of the testicles occurs in two stages, of which the second stage is dependent on androgens. Dependence on androgens also applies to the development of gametes, which continues after birth. Cryptorchidism is currently regarded as endocrinopathy, where the hormonal defect results in an abnormal process of development, which...

The importance and perspectives of stem cells in urology

doc. MUDr. Jozef Marenčák, PhD.

Urol. praxi. 2019;20(2):76-82 | DOI: 10.36290/uro.2019.052  

Stem cells (SCs) are undifferentiated cells that are capable of self-renewal and differentiation and that therefore contribute tothe renewal and repair of tissues. Their capacity for division, differentiation, and tissue regeneration is highly dependent on thesurrounding environment. Several preclinical and clinical studies have utilized SCs in urological disorders. This article is a reviewthe current status of SCs use in benign ang malignant urological diseases and summarizes the results of the preclinical and clinicaltrials that have been conducted.

Andrological care for a patient after spinal cord injury

MUDr. Taťána Šrámková, CSc.

Urol. praxi. 2019;20(2):85-88 | DOI: 10.36290/uro.2019.053  

Sexual health is one of the main priorities for men after traumatic spinal cord injury and the restoration of sexual health is a permanent rehabilitative priority. Men with spinal cord injury require multidisciplinary care, including sexual-andrological care. The sexologist most often intervenes in spinal cord injured men for erectile dysfunction and infertility. In the treatment of erectile dysfunction men after spinal cord injury most often benefits from oral treatment with a phosphodiesterase 5 inhibitors or topically or intracavernosal administered alprostadil. Artificial ejaculation or surgical sperm collection, and assisted reproduction techniques,...

Bilateral testicular microlithiasis in a child with unilateral inguinal testicular retention

prof. MUDr. Vladimír Mihál, CSc., doc. MUDr. Jiřina Zapletalová, Ph.D., MUDr. Kamila Michálková

Urol. praxi. 2019;20(2):89-91  

Testicular microlithiasis (TM) is a rare benign condition with presence of multiple small hyperechogenic microcalcifications inthe seminiferous tubules. Though the aetiology is unknown, TM has been described in association with a variety of urologicalconditions. We report the clinico-radiological features of a 11-year-old boy with bilateral testicular microlithiasis who underwentorchidopexy for left inguinal undescended testis. TM was diagnosed a few days after operation. Family history was negative ontesticular cancer, genital abnormalities and subfertiltiy.

Intraluminal ureteral tumor with hydronephrosis, as presentation of a primary metastatic prostate carcinoma

MUDr. Petr Končický, MUDr. Jan Pokorný, FEBU, MBA, MUDr. Veronika Džundová, MUDr. Aleš Vopelka

Urol. praxi. 2019;20(2):92-93 | DOI: 10.36290/uro.2019.031  

Ureteral metastasis are rare. We present a rare case of intraluminal metastastasis prostate carcinoma in to the ureter.