Urol. praxi. 2023;24(2):64-67 | DOI: 10.36290/uro.2023.041

Hyaluronic acid - use in practical urology

MUDr. Hana Musilová
Urologické oddělení, Slezská nemocnice Opava

Hyaluronic acid is a polysaccharide with various utlization. In urology, hyaluronic acid found its place in many uses. It is applied in prevention of recurrence of lower urinary tract infections, treatment of post-radiation cystitis or in therapy of primary bladder pain syndrome. It is also used in andrology or pediatric urology.

Keywords: hyaluronic acid, prevention of recurrent lower urinary tract infections, post-radiation cystitis, andrology, stress urinary incontinence, urethral stricture, pediatric urology.

Accepted: June 13, 2023; Published: June 15, 2023  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Musilová H. Hyaluronic acid - use in practical urology. Urol. praxi. 2023;24(2):64-67. doi: 10.36290/uro.2023.041.
Download citation

References

  1. Selyanin MA, Boykov P, Khabarov VN. Hyaluronic Acid: Preparation, Properties, Application in Biology and Medicine, First Edition; 2015 John Wiley & Sons, Ltd. Published 2015 by John Wiley & Sons, Ltd.; 17-20. Go to original source...
  2. Iavazzo C, Athanasiou S, Pitsouni E, et al. Hyaluronic acid: an effective alternative treatment of interstitial cystitis, recurrent urinary tract infections, and hemorrhagic cystitis? Eur Urol. 2007;51:1534-1541. https://pubmed.ncbi.nlm.nih.gov/17383810/. Go to original source... Go to PubMed...
  3. Goddard JC, Janssen D. Intravesical hyaluronic acid and chondroitin sulfate for recurrent urinary tract infections:systematic review and meta-analysis. https://pubmed.ncbi.nlm.nih.gov/29181550.
  4. Horňák J, Veselý Š, Havlová K, Babjuk M. Prevence recidivujících cystitid pomocí roztoku hyaluronátu sodného Flaveran®. Ces Urol. 2020;24(3):207-213.
  5. Wyndaele JJ, Riedl C, Taneja R, et al. GAG replenishment therapy for bladder pain syndrome/interstitial cystitis. Neurourology and Urodynamics. 2018;1-10. https://pubmed.ncbi.nlm.nih.gov/30592544/. Go to PubMed...
  6. Lai MC, Kuo YC, Kuo HC. Intravesical hyaluronic acid for interstitial cystitis/painful bladder syndrome: a comparative randomized assessment of different regimens; Int. J. Urol. 2013;20:203-207. https://pubmed.ncbi.nlm.nih.gov/22925498/. Go to original source... Go to PubMed...
  7. Engeler D, Baranowski AP, Berghmans B, et al. EAU Guidelines on Chronic; Pelvic Pain; European Association of Urology. 2023;45:55.
  8. Klečka J. Hyaluronát sodný - prevence a léčba urologické toxicity při onkologické terapii. Urol. praxi. 2021;22(4):181-184. Go to original source...
  9. Gacci M, Saleh O, Giannessi C, et al. Bladder Instillation Therapy With Hyaluronic Acid and Chondroitin Sulfate Improves Symptoms of Postradiation Cystitis: Prospective Pilot Study. Clin. Genitourin. Cancer. 2016;14(5):444-449. doi: 10.1016/j.clgc.2016.01.016. Epub 2016 Feb 8.; https://pubmed.ncbi.nlm.nih.gov/26953222/. Go to original source... Go to PubMed...
  10. Zucchi A, Scroppo FI, Capogrosso P, et al. Clinical use of hyaluronic acid in andrology: A review; Andrology. 2022;10(1):42-50. doi: 10.1111/andr.13083. Epub 2021 Aug 2.; https://pubmed.ncbi.nlm.nih.gov/34297894/. Go to original source... Go to PubMed...
  11. Salonia A, Bettocchi C, Capogrosso P, et al. Verze P. EAU Guidelines on Sexual and Reproductive Health. European Association of Urology. 2023;73:103.
  12. Shebl S, Ali S, Shokr M. Hyaluronic acid injection in the glans penis for the treatment of refractory premature ejaculation: a prospective, controlled study. Andrologia. 2021;53(7):e14084. doi: 10.1111/and.14084. Epub 2021 Apr 30.; https://pubmed.ncbi.nlm.nih.gov/33930204/. Go to original source... Go to PubMed...
  13. Cocci A, Maida FD, Cito G, et al. Comparison of Intralesional Hyaluronic Acid vs. Verapamil for the Treatment of Acute Phase Peyronie's Disease: A Prospective, Open-Label Non-Randomized Clinical Study. World J Mens Health. 2021;27(6):756-762. doi: 10.1089/end.2012.0613. 9: 352. https://pubmed.ncbi.nlm.nih.gov/32009312/. Go to original source... Go to PubMed...
  14. Cai T, Tiscione D, Favilla V, et al. Oral Administration and Intralesional Injection of Hyaluronic Acid Versus Intralesional Injection Alone in Peyronie's Disease: Results from a Phase III Study. World J Mens Health. 2021;39(3):526-532. Published online 2020 Aug 14. doi: 10.5534/wjmh.200048; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255397/. Go to original source...
  15. Kirchin V, Page T, Keegan PE, et al. Urethral injection therapy for urinary incontinence in women. Cochrane Database Syst. Rev, 2012:CD003881;https://pubmed.ncbi.nlm.nih.gov/22336797/. Go to original source...
  16. Chung JH, Kang DH, Choi HY, et al. The effects of hyaluronic acid and carboxymethylcellulose in preventing recurrence of urethral stricture after endoscopic internal urethrotomy: a multicenter, randomized controlled, single-blinded study. J. Endourology. 2013;27(6):756-762. doi: 10.1089/end.2012.0613; https://pubmed.ncbi.nlm.nih.gov/23470209/. Go to original source...
  17. Lumen N, Campos-Juanatey F, Dimitropoulos K, et al. EAU Guidelines on Urethral Strictures. European Association of Urology. 2023;12. Go to PubMed...
  18. Radmayr C, Bogaert G, Burgu B, et al. EAU Guidelines on Paediatric Urology. European Association of Urology. 2023;73. Go to PubMed...




Urology for Practice

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.