Predhovor

prof. MUDr. Dalibor Ondruš, DrSc.

Urol. praxi. 2025;26(1):3-4

Comparision of antimuscarinics and beta-3-mimetics in overactive bladder pharmacotherapy

MUDr. Lenka Plincelnerová

Urol. praxi. 2025;26(1):7-11 | DOI: 10.36290/uro.2025.016

Overactive bladder is a syndrome that leads many patients to visit a urological specialist. Due to its high prevalence in both males and females of any ages, urologist should be well informed about the diagnosis and its treatment. Nowadays, in addition to recommendations of European Association of Urology Guidelines, the treatment tends to be highly individualized. Beside conservative treatment, such as lifestyle changes, pharmacotherapy represents a crucial treatment option. Antimuscarinics are considered a traditional pharmacological choice. Nevertheless, beta-3-mimetics have been successfully used as a combination therapy or even an effective replacement...

The importance of mesh implants in pelvic floor reconstructions in women

MUDr. Miroslav Krhovský

Urol. praxi. 2025;26(1):12-16 | DOI: 10.36290/uro.2025.017

Pelvic floor disorders in women are a very common issue. It is estimated that up to 11% of women are experiencing some form of pelvic organ prolapse (POP). It can hardly be assumed that this statistic will change significantly. Operating technologies are still evolving. Separate colporrhaphys performed in the past are no longer relevant and colpocleisis are indicated rarely. A high rate of unsatisfactory outcomes following conventional surgeries has driven the search for new surgical technologies in this area. Reoperation rates are notably high in countries where relevant clinical trials are ongoing. Olsen et al. report a 29.2% incidence of recurrences,...

Oncological aspects of urolithiasis

doc. MUDr. Jozef Marenčák, PhD.

Urol. praxi. 2025;26(1):17-22 | DOI: 10.36290/uro.2025.018

Urolithiasis is a complex multifactorial disease resulting from interactions between genetic and environmental factors as well as multiple disease states. The debate about whether urinary calculi induce subsequent malignant changes has continued without a consistent conclusion for several decades. Earlier diagnosis of urolithiasis and its appropriate management can prevent/provide a longer time period for the stones to cause chronic irritation of the local environment or for potentially harmful substances dissolved in the urine to apply their carcinogenic effect. The article clearly deals with current knowledge, opinions and hypotheses in the issue...

Role of genetic testing at the deciding about the treatment of the kidney tumors

MUDr. Robert Novák, MUDr. Jana Katolická, Ph.D.

Urol. praxi. 2025;26(1):40-45 | DOI: 10.36290/uro.2025.023

Renal cell carcinoma (RCC) is a histologically diverse disease, with variable and often unpredictable clinical behavior. Gene expression profiling is a promising technique for refining the diagnosis and staging of RCC, as well as for highlighting potential therapeutic targets (1).

Metabolic syndrome nad urinary track disorders

prof. MUDr. Miroslav Merta, CSc.

Urol. praxi. 2025;26(1):46-50 | DOI: 10.36290/uro.2025.024

Metabolic syndrome (MetS) is a complex unit of various metabolic disorders, inclu­ding abdominal obesity, dyslipidemia, elevated blood pressure and increased fasting glycemia, which act in mutual interplay as important risk factors for multiple diseases, including disorders of urinary tract. Increasing body of evidence suggest that MetS and its individual components predispose not only to the development of malignant tumors notably carcinoma of kidney, prostate, ureter or urinary bladder but also to the development of other urological diseases, such as urolithiasis, benign prostate hypertrophy, male hypogonadism or erectile dysfunction. Some patophysiological...

Vitamin D and its impact on sexual and reproductive health

MUDr. Pavel Turčan, Ph.D., FECSM, MUDr. Peter Kepič, MUDr. Jozef Hambálek, MUDr. Pavla Entnerová

Urol. praxi. 2025;26(1):23-27 | DOI: 10.36290/uro.2025.019

Vitamin D plays a very significant role in human health. Its deficiency is associated with many health complications. However, its influence on reproduction and sexual function in both men and women is generally less known. This article provides an overview of this issue and informs about the possibilities of vitamin D supplementation. Vitamin D supplementation is beneficial for health and quality of life in almost all areas. The most effective treatment is with prescription drugs. A new treatment option with calcifediol is an even more effective and safer choice.

Disorders of ejaculation in urological diseases

MUDr. Marcela Fontana, Ph.D., FEBU

Urol. praxi. 2025;26(1):28-31 | DOI: 10.36290/uro.2025.020

Difficulties with ejaculation are particularly common among urological patients and often lead to deterioration in quality of sexual life and partnership. Yet are often not disussed. Unfortunatelly, not always are influenceable. Patients should be properly informed about possible negative effects of urological medication or surgical procedures on ejaculation. The following text focuses on anejaculation, retrograde ejaculation, delayed ejaculation and painful ejaculation.

Hematuria - differential diagnosis

MUDr. Eva Myslivečková, prof. MUDr. Ivan Rychlík, CSc., FASN, FERA, FISN

Urol. praxi. 2025;26(1):35-38 | DOI: 10.36290/uro.2025.022

Hematuria is a symptom of kidney and urinary tract disease. It is important to prove the presence of hematuria and at the same time assess its intensity and origin. Hematuria is classified by quantity into macroscopic and microscopic, and by origin into glomeru­lar (in primary and secondary glomerulonephritis) and non-glomerular (in diseases affecting the kidney parenchyma other than glomeruli, postrenal or extrarenal causes). Diseases causing hematuria also include serious or rapidly progressing conditions that require prompt diagnosis assessment and intervention, either by a urologist or a nephrologist. Therefore, the correct differential diagnosis...

An unfortunate experiment with mounting foam

MUDr. Michaela Železníková, MUDr. Miroslav Krhovský

Urol. praxi. 2025;26(1):51-53 | DOI: 10.36290/uro.2025.025

Many foreign bodies in urinary tract have been documented. These cases are commonly encountered in almost all urology departments, some of which are quite curious. We present an interesting case report of an unusual foreign body in urinary tract from our workplace.

Local treatment of wounds and lesions in the genitoanal area in women with regard to the effectiveness of the dressing and the comfort of the patient

Mgr. Markéta Koutná, Ph.D.

Urol. praxi. 2025;26(1):54-58 | DOI: 10.36290/uro.2025.026

This article deals with the issue of the spectrum of therapeutic materials suitable for the treatment of wounds, ulcerations and lesions in the genitoanal area in women. Despite the fact that the content of the article is primarily dedicated to the female genitoanal area, the described local therapy is also applicable to men in the same region. Histologically, the female and male genitalia consist of identical tissues, which are distinguished only by anatomical features. Damage to the genitoanal area requires materials for repeated application during the day, are affordable, relieve pain and improve comfort of patients. The illustrative scheme in the...

Role of beetroot prior to ordering repeat prostate biopsy

MUDr. Šárka Kudláčková, Ph.D.

Urol. praxi. 2025;26(1):33-34 | DOI: 10.36290/uro.2025.021

In patients with chronic abacterial prostatitis and elevated PSA, beetroot aids in the treatment of inflammation, thus reducing the PSA level. In addition to relieving patients from the symptoms of chronic prostatitis, the decrease in PSA that is associated with reduction of inflammation may ultimately render prostate rebiopsy unnecessary in the patient.