Urol. praxi. 2017;18(5):228-232 | DOI: 10.36290/uro.2017.053

Penile curvature and its treatment

MUDr. Pavel Turčan
Centrum MEDIOL, s. r. o., Olomouc

Penile curvature are congenital or acquired. Congenital curvatures without hypospadia usually do not require a solution. The mostcommon cause of the acquired curvature is Peyronie's disease. It is a penile disorder with fibrous plaque in the tunica albuginea,which is manifested by pain, curvature, constriction or shortening of the penis and is particularly evident in the penis in the erectstate. Treatment is complicated and requires the patience of the patient and the doctor. The article focuses primarily on the conservativepossibilities of therapy, we bring an overview of individual methods and their effectiveness.

Keywords: curvature of the penis, Peyronie´s disease, induratio penis plastica, intralesional injection

Published: December 1, 2017  Show citation

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Turčan P. Penile curvature and its treatment. Urol. praxi. 2017;18(5):228-232. doi: 10.36290/uro.2017.053.
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References

  1. Študent V, Záťura F, Mucha Z. Základy urologické andrologie. Praha: Galén 2003: 160 s.
  2. Yachia D, Beyar M, Aridogan IA, et al. The Incidence of Congenital Penile Curvature. J Urol 1993; 150: 1478-1479. Go to original source... Go to PubMed...
  3. Montag S, Palmer LS. Abnormalities of Penile Curvature: Chordee and Penile Torsion. Scientific World Journal 2011; 11: 1470-1478. Go to original source... Go to PubMed...
  4. Kramer S, Aydin G, Kelalis P. Chordee without hypospadias in children. J Urol 1982; 128: 559-561. Go to original source... Go to PubMed...
  5. Cruz N. Congenital penile curvature and penile torsion. In: Porst H, Reisman Y. The ESSM Syllabus of Sexual Medicine. Medix Publishers Amsterdam 2012: 747-764.
  6. Darewicz B, Kudelski J, Szynaka B, et al. Ultrastucture of the tunica albuginea in congenital penile curvature. J Urol 2001; 166 (5): 1766-1768. Go to original source... Go to PubMed...
  7. Wespes E, Hatzimouratidis K, Eardley I, et al. Guidelines EAU pro léčbu zakřivení penisu. Urol List 2013; 11(1): 65-77.
  8. Mašková V, Palascak P, Gomez-Orosco W, et al. Vrozená laterální deformace penisu. Urol praxi 2006; 3: 128-129.
  9. Vidlář A, Hartmann I, Hrabec M, et al. Následky pokusu o manuální autokorekci lehkého zakřivení penisu. Urol praxi 2009; 10(1): 39-40.
  10. Zámečník L. Urologická problematika v sexuologii. In Weiss P, et al. Sexuologie. Grada Praha 2010: 161-175.
  11. Urbánek V. Poranění mužského těla během pohlavního styku. Moderní babictví 2004; 3.
  12. Cruz N. Injuries to penis and testicles. In: Porst H, Reisman Y, et al. The ESSM Syllabus of Sexual Medicine, Amsterdam, MEDIX, 2012: 644-660.
  13. Kubíček V. Současný stav léčby Peyronieho choroby. Urol praxi 2003; 3: 11-13.
  14. Turčan P. Mužské sexuální dysfunkce. In: Turčan P, Pokorný P, Fait T. Sexuologie pro urology a gynekology. Maxdorf Praha; 2012: 142-182.
  15. Levine LA, Taylor FL. Peyronieho choroba. Urol List 2008; 6(4): 5-17.
  16. Mulhall JP, Creech SD, Boorjian SA, et al. Subjective and objective analysis of the prevalence of Peyronie's disease in a population of men presenting for prostate cancer screening. J Urol 2004; 171: 2350-2353. Go to original source... Go to PubMed...
  17. Deveci S, Hopps CV, O'Brien K, et al. Defining the clinical characteristics of Peyronie's disease in young men. J Sex Med 2007; 4(2): 485-490. Go to original source... Go to PubMed...
  18. Carrieri MP, Serraino D, Palmiotto F, et al. A case-control study on risk factors for Peyronie's disease. J Clin Epidemiol 1998; 51(6): 511-515. Go to original source...
  19. Sommer F, Schwarzer U, Wassmer G, et al. Epidemiology of Peyronie's disease. Int J Impot Res 2002; 14(5): 379-383. Go to original source...
  20. Mulhall JP, et al. An analysis of the natural history of Peyronie's disease. J Urol 2006; 175(6): 2115-2118; discussion 2118. Go to original source... Go to PubMed...
  21. Porst H. An overview of pharmacotherapy in premature ejaculation. J Sex Med. 2011; 8 Suppl 4: 335-341. Go to original source...
  22. Hatzimouratidis K, Hatzichristou D. Sexual dysfunction: Classifications and Definitions. J Sex Med. 2007; 4: 241-250. Go to original source... Go to PubMed...
  23. Horák A. Peyronieho choroba. Ces Urol 2017; 21(1): 43-58.
  24. Hatzimouratidis K, Eardley I, Giuliano F, et al. EAU guidelines on penile curvature. Eur Urol 2012 Sep; 62(3): 543-552. Go to original source... Go to PubMed...
  25. Nehra A, Alterowitz R, Culkin DJ, et al. Peyronie's disease: AUA guideline. American Urological Association 2015 [online]. [cit. 2017-08-30]. Dostupný v nezkrácené verzi na https://www.auanet.org/guidelines/peyronies-disease-(2015).
  26. Shindel AW, et al. Urologist practice patterns in the management of Peyronie's disease: a nationwide survey. J Sex Med 2008 5(4): 954-964. Go to original source... Go to PubMed...
  27. Barret Harlow B, Wang R. Oral therapy for Peyronies's disease, does it work? Transl Androl Urol. 2016; 5(3): 296-302. Go to original source... Go to PubMed...
  28. Weidner W, et al. Potassium paraaminobenzoate (POTABA) in the treatment of Peyronie's disease: a prospective, placebo-controlled, randomized study. Eur Urol 2005 47(4): 530-535; discussion 535-536. Go to original source... Go to PubMed...
  29. Teloken C, et al. Tamoxifen versus placebo in the treatment of Peyronie's disease. J Urol 1999 162(6): 2003-2005. Go to original source... Go to PubMed...
  30. Safarinejad MR. Therapeutic effects of colchicine in the management of Peyronie's disease: a randomized doubleblind, placebo controlled study. Inf J Impot Res 2004; 16: 238. Go to original source... Go to PubMed...
  31. Shindel AW, et al. Pentoxifylline attenuates transforming growth factor-beta1-stimulated collagen deposition and elastogenesis in human tunica albuginea-derived fibroblasts part 1: impact on extracellular matrix. J Sex Med 2010 7(6): 2077-2085. Go to original source... Go to PubMed...
  32. Trost LW, Gur S, Hellstrom WJ.Pharmacological management of Peyronie's didease. Drugs 2007; 67: 527. Go to original source... Go to PubMed...
  33. Tranchant C, et al. Mechanism of action of glucocorticoids: role of lipocortins. Rev Neurol (Paris) 1989; 145(12): 813-818.
  34. Bennett NE, et al. Intralesional verapamil prevents the progression of Peyronie's disease. Urology 2007; 69(6): 1181-1184. Go to original source... Go to PubMed...
  35. Turčan P, Pokorný P. Naše zkušenosti s využitím léčby rázovou vlnou při řešení intimních potíží mužů. In: XXVII. Bohnické sexuologické dny 26.-27. 2. 2015. Brno 2016: Akademické nakladatelství CERM: 75-76.
  36. Peyronieho choroba. Kontakt na nejbližšího odborníka [online]. [cit. 2017-08-31]. Dostupné na http://www.peyroniehochoroba.cz/.
  37. Hellstrom WJ, et al. Single-blind, multicenter, placebo controlled, parallel study to assess the safety and efficacy of intralesional interferon alpha-2B for minimally invasive treatment for Peyronie's disease. J Urol 2006; 176(1): 394-398. Go to original source... Go to PubMed...
  38. Zámečník L, Korousová M. Plastická indrurace penisu - lokální léčba verapamilem. Urol praxi 2009; 10(2): 69-71.
  39. Martin DJ, et al. Transdermal application of verapamil gel to the penile shaft fails to infiltrate the tunica albuginea. J Urol 2002; 168(6): 2483-2485. Go to original source... Go to PubMed...
  40. Greenfield JM, et al. Verapamil versus saline in electromotive drug administration for Peyronie's disease: a double-blind, placebo controlled trial. J Urol 2007; 177(3): 972-975. Go to original source... Go to PubMed...
  41. Palmieri A, et al. A first prospective, randomized, double-blind, placebo-controlled clinical trial evaluating extracorporeal shock wave therapy for the treatment of Peyronie's disease. Eur Urol 2009; 56(2): 363-369. Go to original source... Go to PubMed...
  42. Mirone V, Imbimbo C, Palmieri A, et al. Our experience on the association of a new physical and medical therapy in patients suffering from induratio penis plastica. Eur Urol 1999; 36: 327-330. Go to original source... Go to PubMed...
  43. Carrieri MP, et al. A case-control study on risk factors for Peyronie's disease. J Clin Epidemiol 1998; 51(6): 511-515. Go to original source...
  44. Gholami SS, Lue TF. Correction of penile curvature using the 16dot plication technique: a review of 132 patients. J urol 2002; 167: 2066. Go to original source... Go to PubMed...
  45. Hellstrom WJ, Usta MF. Surgical approaches for advances Pyeronie's disease patients. Int J Impot Res 2003; 15(Suppl 5): S121. Go to original source...
  46. Bittner L, Zámečník L. No touch technika v implantaci penilních protéz významně snižuje riziko infekce. Ces Urol. 2016; 20(3)(suppl. A): 46.
  47. Carson CC. Penile prosthesis implantation in the treatment of Peyronie's disease and erectile dysfunction. Int J Impot Res 2000; 12(suppl 4): 122. Go to original source...




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