Urol. praxi. 2017;18(2):73-76 | DOI: 10.36290/uro.2017.016

Testosteron replacement therapy in daily urological practise

MUDr. Aleš Horák
ANDROPHARM medical, s.r.o., Ostrava

Currently, when there is a general increase in life expectancy, demands on improving its quality have increased. Low levels of testosterone

in a man of a given age may be associated with subjectively perceived discomfort, sexual dysfunction and cardiovascular

risk. Based on patient's subjective symptoms and testosterone levels, testosterone replacement therapy (TRT) may be initiated.

Keywords: testosteron, quality of life, cardiovaskular risc, testosteron replacement therapy

Published: May 1, 2017  Show citation

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Horák A. Testosteron replacement therapy in daily urological practise. Urol. praxi. 2017;18(2):73-76. doi: 10.36290/uro.2017.016.
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    References

    1. Randeva HS, Davison RM, Bouloux PMG, Endocrinology In: Carson CC, Kirby RS, Goldstein I. Textbook of erectie dysfunction. Isis Medical Media Oxford 1999: 89-104.
    2. Dohle GR, Arver S, Bettocchi C, Jones TH, Kliesch S, Punab M. Guidelines on Male Hypogonadism [online]. Dostupný z http://uroweb.org/wp-content/uploads/EAU-Guidelines-Male-Hypogonadizm-2015.pdf.
    3. Horák A. Androgenní deficit u stárnoucích mužů a ilustrační kazuistika. Urol List 2006; 4(1): 2-5.
    4. Verner AA. The Male Climacteric. JAMA 1939; 112: 1441-1443. Go to original source...
    5. Kaufmann JM, Vermeulen A. Declining Gonadal Function in Elderly Men. Bailliere's Clin Endocr Metab 1997; 11: 289-309. Go to original source... Go to PubMed...
    6. Vermeulen A, Kaufman JM. Editorial: Role of the Hypothalomo-pituitary. Function in the Hypoandrogenism of Healthy Aging. J Clin Endocrinol Metab 1992; 74: 1226 A-C. Go to original source... Go to PubMed...
    7. Vermeulen A. The Male Climacterium. Ann Med 1993; 25: 531-534. Go to original source...
    8. Stárka L. Pohled endokrinologa na mužské stárnutí. Andrologie 2000; 2: 1-10.
    9. Kubíček V. Hormonální prostředí stárnoucího muže a hormonální substituční terapie. Andrologie 2000; 2: 22-28.
    10. Doleček R. Endocrine Profile Of the Aging (old) Man. Results of a 15-Year Study. Abstract From the First Congress of the FEMS. Pratur 2000: 189-211.
    11. Davidson JM, Chen JJ, Grapo L, et al. Hormonal Changes and Sexual Function in Aging Men. J Clin Endocrin Metab 1983; 57: 71-77. Go to original source... Go to PubMed...
    12. Jockenhövel F, Kaufman JM, Mickisch GH, et al. The good, the bad, and the unknown of late - onset hypogonadism: the urological perspective. JMHG 2005; 3: 292-301. Go to original source...
    13. Otakar Š. Substituční léčba testosteronemu hypogonadálních mužů. Urol. praxi 2015; 16(1): 12-15.
    14. Rao P, Brooke JC, Walter D, et al. Testosterone replacement therapy has beneficial effects on cardiovascular risk factors and liver function in hypogonadal men. Endocrine Rev. 2013; 34(3 Meeting Abstracts): SAT-573.
    15. Sharma R, et al. Normalization of testosterone level is associated with reduced incidence of myocardial infarction and mortality in men [online]. Dostupný z http://dx.doi.org/10.1093/eurheartj/ehv3462706-2715
    16. Horák A. Substituční terapie testosteronem a kardiovaskulární riziko. Urol. praxi, 2016, 17(1): 23-26. Go to original source...
    17. Burns-Cox N, Gingell JC. Erectile dysfunction: Endocrinological therapies,risks and benefits of treatment, Endocrinology. In: Carson CC, Kirby RS, Goldstein I. Textbook of erectie dysfunction. Isis Medical Media Oxford 1999: 327-344.
    18. Morales A, Lunenfeld B. Investigation, treatment and monitoring of late - onset hypogonadism in males (Official Recommendations of ISSA). Aging Male 2002; 5: 74-86. Go to original source... Go to PubMed...
    19. Nieschlag E, Swerdloff R, Behre HM, et al. Investigation, treatment and monitoring of late - onset hypogonadism in males official recommendations of ISA, ISSAM, and EAU recommendations. Eur Urol 2005; 48: 1-4. Go to original source... Go to PubMed...
    20. Lunenfeld B, Mskhalaya G, Zitzmann M, et al. Recommendations on the diagnosis, treatment and monitoring of hypogonadism in men [online]. Dostupné z http://www.issam.ch/guidlines_art.
    21. Kubíček V. Racionální substituční terapie androgeny u muže. Andrologie 2000; 1(Suppl): 3-9. Go to PubMed...
    22. Kubíček V, Nové léky v andrologii. Urol. praxi 2016; 17(2): 79-83. Go to original source...
    23. Khera M, Adaikan C, Buvat J, et al. Diagnosis and treatment of testosterone deficiency: Recommendations from the fourth international Consultation for sexual medicine (ICSM 2015), J Sex Med 2016? 13: 1787-1804. Go to original source...
    24. Morgentaler A. Testosterone Therapy and Cardiovascular Risks [online]. Dostupný z http://www.prizmhealthonline.com/lms/mod/page/view.php?id=196
    25. Testosteron - Výbor PRAC nepotvrdil zvýšené riziko kardiovaskulárních nežádoucích účinků [online]. Dostupný z http://www.sukl.cz/testosteron-vybor-prac-nepotvrdil-zvysene-riziko
    26. Nieschlag E. Testosteron Replacement Therapy: Something Old, Something New. Clin Endocrin 1996; 45: 261-262. Go to original source... Go to PubMed...
    27. Morales A. Andropause (or symptomatic late-onset hypogonadism): facts, fiction and controversies. Aging Male 2004; 7: 1-7. Go to original source... Go to PubMed...
    28. Shankar U, Roberts SA, Connolly MJ, et al. Effects of testosterone on muscle strength, physical function, body composition, and quality of life in intermediate-frail and frail elderly men: a randomized, double-blind, placebo-controlled study. J Clin Endocrinol Metab. 2010; 95(2): 639-650. Go to original source...

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