Urol. praxi, 2012; 13(1): 34-38

Ionizing radiation and renal cell cancer

Mgr.Kateřina Azeem¹, doc.MUDr.Helena Kollárová, Ph.D.¹, doc.MUDr.Richard Reif, CSc.², Ing.Hana Tomášková, Ph.D.³, MUDr.Dagmar Horáková, Ph.D.¹, prof.MUDr.Vladimír Janout, CSc.¹

¹ Ústav preventivního lékařství, Lékařská fakulta, Univerzita Palackého v Olomouci

² Urologická klinika, Lékařská fakulta, Univerzita Palackého v Olomouci

³ Ústav epidemiologie a ochrany veřejného zdraví, Lékařská fakulta, Ostravská univerzita, Ostrava

Backgrounds: Renal cell cancer is one of the 10 most common cancers in our country and abroad. The main risk factors for RCC include

smoking, obesity, hypertension and family disposition. One other factor is exposure to ionizing radiation.

Materials and methods: Study consisted of 635 persons, of which 300 cases and 335 controls. From both cases and controls was obtained

level of exposure to ionizing radiation, focusing on the number of X-ray examinations in related to work classification, radiation

for medical reasons and in women, whether and how often undergo they mammography.

Results: When evaluating the number of X-ray examination related to employment status was found significant associations with

kidney cancer. The irradiation for medical reason suggested only trend at association of irradiation and increased risk of kidney cancer,

a statistically insignificant result was probably due to small sample size. Originally outlined inverse association of mammography and

kidney cancer was not confirmed after the division into groups according to the number performed examinations.

Conclusions: Ionizing radiation is a weak risk factor for kidney cancer. For a more detailed analysis of the effects of ionizing radiation

would be more appropriate type of prospective study.

Keywords: renal cell cancer, ionizing radiation, X-rays, mammography

Published: February 15, 2012  Show citation