Urol. praxi, 2011; 12(4): 234-237

Fournier gangrene in present urological practice

MUDr.Ivan Kolombo, FEBU1, MUDr.Martina Poršová2, MUDr.Richard Pabišta2, MUDr.Jaroslav Porš3, MUDr.Jiří Poněšický1, MUDr.Přemysl Grubský2, MUDr.Jan Zaplatílek2, MUDr.Robert Šverma2, MUDr.Leoš Gronka3, MUDr.Milan Bartůněk1
1 Centrum robotické chirurgie a urologie, Nemocnice Na Homolce Praha
2 Urologické oddělení, Nemocnice Mladá Boleslav
3 Urologická poradna, Městská nemocnice Turnov

Fournier gangrene, is defined as a polymicrobial soft-tissue necrotizing infections of the perineal, perianal, or genital areas. It is rare

infection of the genitalia that is associated with high morbidity and mortality. Fournier gangrene nowadays has an identifiable cause

in approximately 95 % of cases. The necrotizing process commonly originates from an infection in the anorectum, the urogenital tract,

or the skin of the genitalia. Treatment of Fournier gangrene involves several modalities. Initiate early broad-spectrum antibiotics as soon

as possible. Providing coverage for gram-positive, gram-negative, aerobic, and anaerobic bacteria is essential. Early surgical therapy is

also essetial and all necrotic tissue must be excised. The use of vacuum dressing technologies – VAC (Vacuum-assisted closure) holds the

potential to promote faster wound healing after debridement procedure. Interdisciplinary approach is a necessary and important for

patients with Fournier´s gangrene.

antibiotics, surgical therapy, wound healing – Vacuum-assisted closure (VAC) therapy, interdisciplinary approach.

Keywords: Fournier gangrene, Fournier’s disease, genital infections, necrotizing fasciitis, aerobic and anaerobic bacteria, intensive care,

Published: August 10, 2011  Show citation

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Kolombo I, Poršová M, Pabišta R, Porš J, Poněšický J, Grubský P, et al.. Fournier gangrene in present urological practice. Urol. praxi. 2011;12(4):234-237.
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References

  1. Dvořáček J. Infekce močového ústrojí. In: Dvořáček J. Urologie praktického lékaře. ISV Praha, 2000; 101-116.
  2. Eichenauer RH, Vanharpe H. Kritické stavy. In: Eichenauer RH, Vanharpe H. Urologie - klinika a praxe. Praha: SCIENTIA MEDICA, spol. s.r.o., 1996: 94.
  3. Fournier JA. Gangr?ne-foudroyante de la verge. Semin Med 1883; 3: 345.
  4. Stephens BJ, Lathrop JC, Rice WT, Gruenberg JC. Fournier´s gangrene historic (1764-1978) versus contemporary (1979-88) differences in etiology and clinical importance. Ann Surg 1993; 59: 149-154.
  5. Kolombo I, Hanuš T, Porš J, Poršová M, Pabišta R, et al. Infekce močových cest pro praktické lékaře a specialisty. Praha: Galén, 2007: 1-281.
  6. Cohen MS. Fournier's gangrene. AUA Update Series 1986; 5(6).
  7. Miller JD. The importance of early diagnosis and surgical treatment of necrotizing fasciitis. Surg Gynecol Obstet 1983; 157: 197.
  8. Loulergue P, Mahe V, Bougnoux ME, Poiree S, Hot A, Lortholary O. Fournier's gangrene due to Candida glabrata. Med Mycol. Mar 2008; 46(2): 171-173. Go to original source... Go to PubMed...
  9. Akcan A, Sozuer E, Akyildiz H, Yilmaz N, Kucuk C, Ok E. Necessity of preventive colostomy for Fournier's gangrene of the anorectal region. Ulus Travma Acil Cerrahi Derg 2009; 15(4): 342-346. Go to PubMed...
  10. Akita H, Hayashi J, Kojima M. Fournier´s gangrene in a patient with perirectal abscess: a case report. Hinyokika - Kiyo 1995; 41: 633-635. Go to PubMed...
  11. Gerber GS, Guss SP, Pielet RW. Fournier´s gangrene secondary to intraabdominal processes. Urology 1994; 44: 779-782. Go to original source... Go to PubMed...
  12. Katan S, Youssef A. Fournier´s gangrene of the scrotum folowing anorectal disorders. Int Urol Nefrol 1994; 26(2): 215-222. Go to original source... Go to PubMed...
  13. Kolombo I. Pohledy na diagnostiku a léčbu perirektálních abscesů. Atestační práce. Katedra chirurgie IPVZ Praha, 1997.
  14. Picramenos D, Deliveliotis C, Macrichoritis K, Alexopulon K, Kostakopoulos A, Dimopoulos C. Fournier´s gangrene: etiology, treatment and complications. Prog Urol 1995; 5: 701-705. Go to PubMed...
  15. Spirnak JP, Resnick MI, Hampel N, Persky L. Fournier´s gangrene report of 20 patients. J Urol 1984; 131: 289-291. Go to original source... Go to PubMed...
  16. Eke N. Fournier´s gangrene, the Nigerian experience. Nig Postgrad Med J 1999; 6: 99-102.
  17. Ameh EA, Dauda MM, Sabiu L, Mshelbwala PM, Mbibu HN, Nmadu PT. Fournier's gangrene in neonates and infants. Eur J Pediatr Surg 2004; 14(6): 418-421. Go to original source... Go to PubMed...
  18. Eke N. Fournier´s gangrene: a review of 1726 cases. Br J Surg 2000; 87: 718-728. Go to original source... Go to PubMed...
  19. Kočvara R. Pediatrická andrologie. In: Dvořáček J, a kol. Urologie, díl III. Praha ISV, 1998: 1389-1402.
  20. Redman JF, Yamauchi T, Higginbothom WE. Fournier´s gangrene of the scrotum in a child. J Urol 1979; 121: 827. Go to original source... Go to PubMed...
  21. Ekelius L, Björkman H, Kalin M, Fohlman J. Fournier's gangrene after genital piercing. Scand J Infect Dis. 2004; 36(8): 610-612. Go to original source... Go to PubMed...
  22. Mouraviev VB, Pautler SE, Hayman WP. Fournier's gangrene following penile self-injection with cocaine. Scand J Urol Nephrol. 2002; 36(4): 317-318. Go to original source... Go to PubMed...
  23. Jamieson NV, Everett WG, Bullock KN. Delayed recognition of intersphincteric abscess as underlying case of Fournier's scrotal gangrene. Ann R Coll Surg Engl 1984; 66: 434. Go to PubMed...
  24. Quatan N, Kirby RS. Improving outcomes in Fournier´s gangrene. BJU Int 2004; 93(6): 691-692. Go to original source... Go to PubMed...
  25. Corman JM, Moody JA, Aronson WJ. Fournier´s gangrene in a modern surgical setting: improved survival with aggressive management. BJU Int 1999; 84: 85-88. Go to original source... Go to PubMed...
  26. Paty R, Smith AD. Gangrene and Fournier's gangrene. Urol Clin North Am 1992; 19: 149. Go to original source... Go to PubMed...
  27. Stamenkovic I, Lew PD. Early recognition of potentially fatal necrotizing fasciitis: The role of frozen section biopsy. N Engl J Med 1984; 310: 1689. Go to original source... Go to PubMed...
  28. Laor E, Palmer LS, Tolia BM, Reid RE, Winter HI. Outcome prediction in patients with Fournier´s gangrene. J Urol 1995; 154: 89-92. Go to original source... Go to PubMed...
  29. Schaeffer AJ. Infections of the urinary tract. In: Campbell´s Urology CD-Rom, Walsh PC, Retik AB, Vaughan ED, Wein AJ, Volume 1, Section 4, Chapter 14, Copyright 2002, Elsevier Science (USA).
  30. Kolombo I, Kolombová J, Beňo P, Toběrný M, a kol. Mezioborová spolupráce v urologii. Urolog. Praxi 2007; 8(6): 262-267.
  31. Cawley MJ, Briggs M, Haith LR Jr, Reilly KJ, Guilday RE, Braxton GR. Intravenous immunoglobulin as adjunctive treatment for streptococcal toxic shock syndrome associated with necrotizing fasciitis: case report and review. Pharmacotherapy. Sep 1999; 19(9): 1094-1098. Go to original source... Go to PubMed...
  32. Mindrup SR, Kealey GP, Fallon B. Hyperbaric oxygen for the treatment of fournier's gangrene. J Urol. Jun 2005; 173(6): 1975-1977. Go to original source... Go to PubMed...
  33. Kovacs LH, Kloeppel M, Papadopulos NA, Reeker W, Biemer E. Necrotizing fasciitis. Ann Plast Surg. Dec 2001; 47(6): 680-682. Go to original source... Go to PubMed...
  34. Baskin LS, Carroll PR, Cattolica EV, et al. Necrotizing soft tissue infections of the perineum and genitalia: Bacteriology, treatment, and risk assessment. Br J Urol 1990; 65: 524. Go to original source... Go to PubMed...
  35. Clayton MD, Fowler JE Jr, Sharifi R. Causes, presentation, and survival of 57 patients with necrotizing fasciitis of the male genitalia. Surg Gynecol Obstet 1990; 170: 49.
  36. Grabe M, Bjerkland-Johansen TE, Botto H, et al. Guidelines on Urological Infections. 2011 edition. Update March 2011.




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