Urol. praxi, 2011; 12(4): 203-207

LDUH.

MUDr.Michaela Matoušková, doc.MUDr.Miroslav Hanuš, CSc.
Urocentrum Praha

Thromboprophylaxis in urologic and oncologic urologic surgery

The increasing extent and radicality of surgical procedures, particularly in at-risk patients, increasingly requires adequate prophylactic

measures in preventing venous complications. Urologic and, in particular, oncologic urologic surgery is burdened by a high risk of

developing deep vein thrombosis and pulmonary embolism. The introduction of rational thromboprophylaxis reduces this risk and improves

the patient‘s prognosis. Routine use of appropriate thromboprophylaxis and its prolongation should be included in the standard

algorithms for care in urologic and oncologic urologic patients.

Keywords: deep vein thrombosis, pulmonary embolism, low molecular weight heparins – LMWH, low-dose unfractionated heparin – LDUH

Published: August 10, 2011  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Matoušková M, Hanuš M. LDUH. Urol. praxi. 2011;12(4):203-207.
Download citation

References

  1. Vaitkus PT, Leizorovicz A, Cohen AT, et al. PREVENT medical tromboprophylaxis study group mortality rates and risk factors for asymptomatic deep vein trombosis in medical patients. J Tromb Haemost 2005; 93(1): 76-79. Go to original source... Go to PubMed...
  2. Cohen AT, Tapson VF, Bergmann JF, et al. Venous tromboembolism risk and profylaxis in the acute hospital care setting (ENDORSE study): a multinational cross- sectional study. Lancet 2008; 371: 387-394. Go to original source... Go to PubMed...
  3. Mismetti P, Laporte S, Darmon JY, et al. Meta-analysis of low molecular weight heparin in the prevention of venous thromboembolism in general surgery. Br J Surg 2001; 88: 913-930. Go to original source... Go to PubMed...
  4. Claget GP, Reisch JS. Prevention of venous thromboembolism in general surgical patients: results of meta-analysis. Ann Surg 1988; 208: 227-240. Go to original source... Go to PubMed...
  5. Pezzuoli G, Neri Serneri GG, Settembrini P, et al. Prophylaxis of fatal pulmonary embolism in general surgery using low-molecular-weight heparin Cy 216: a multicentre, doubleblind, randomized, controlled, clinical trial versus placebo (STEP). Int Surg 1989; 74: 205-210. Go to PubMed...
  6. Malý J, Dulíček P, Blažek M, et al. Trombofilní stavy - laboratorní a klinická diagnostika. Interv Akut Kardiol 2007; 6(Suppl B): B11-B16.
  7. Geerts WH, Bergquist D, Pineo GF, et al. Prevention of Venous Thromboembolism: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest 2008; 133; 381-453. http://chestjournal.org/cgi/content/abstract/133/6_suppl/381S. Go to original source...
  8. Nicolaides A, Irving D, Pretzell M, et al. The risk of deepvein thrombosis in surgical patients. Br J Surg 1973; 60: 312.
  9. Riber C, Alstrup N, Nymann T, et al. Postoperative thromboembolism after day-case herniorrhaphy. Br J Surg 1996; 83: 420-421. Go to original source... Go to PubMed...
  10. Hendolin H, Mattila MAK, Poikolainen E. The effect of lumbar epidural analgesia on the development of deep vein thrombosis of the legs after open prostatectomy. Acta Chir Scand 1981; 147: 425-429. Go to PubMed...
  11. Nicolaides AN, Bergqvist D, Hull R, et al. Prevention of venous thromboembolism: International konsensus statement. Int Angiol 1997; 16: 3-38. Go to PubMed...
  12. Collins R, Scrimgeour A, Yusuf S, et al. Reduction in fatal pulmonary embolism and venous thrombosis by perioperative administration of subcutaneous heparin: overview of results of randomized trials in general, orthopedic and urologic surgery. N Engl J Med 1988; 318: 1162-1173. Go to original source... Go to PubMed...
  13. Heit JA, Silverstein MD, Mohr DN, et al. The epidemiology of venous thromboembolism in the community. Thromb Haemost 2001; 86: 452-463. Go to original source... Go to PubMed...
  14. Heit JA, O'Fallon WM, Petterson TM, et al. Relative impal of risk factors for deep vein thrombosis and pulmonary embolism: a population-based study. Arch Intern Med 2002; 162: 1245-1248. Go to original source... Go to PubMed...
  15. Lindblad B, Eriksson A, Bergqvist D. Autopsy-verified pulmonary embolism in a surgical department: analysis of the period from 1951 to 1988. Br J Surg 1991; 78: 849-852. Go to original source... Go to PubMed...
  16. Rasmussen MS. Preventing thromboembolic complication in cancer patients after surgery: a role for prolonged thromboprophylaxis. Cancer Treat Rev 2002; 28: 141-144. Go to original source... Go to PubMed...
  17. Rasmussen MS, Willie-Jorgensen P, Jorgensen LN, et al. Prolonged thrombopro- phylaxis with low molecular weight heparin (dalteparin) following major abdominal surgery for malignancy (abstract). Blood 2003; 102: 56a.
  18. Leizorovicz A, Haugh MC, Chapuis FR, et al. Low molecular weight heparin in prevention of perioperative thrombosis. BMJ 1992; 305: 913-920. Go to original source... Go to PubMed...
  19. Lyman, et al. American Society of Clinical Oncology Guideline: Recommendations for Venous Thromboembolism Prophylaxis and Treatment in Patients With Cancer. J Clin Oncol 2007: 25(34): 5490-5505. Go to original source... Go to PubMed...
  20. Mandala, et al. Venous thromboembolism in cancer patients: ESMO Clinical Practice Guidelines for the management. clinical practice guidelines. Annals of Oncology 21 (Supplement 5): v274-v276, 2010. doi: 10.1093/annonc/mdq199. Go to original source... Go to PubMed...
  21. White RH, Zhou H, Romano PS. Incidence of symptomatic venous thromboembolism after different elective or urgent surgical procedures. Thromb Haemost 2003; 90: 446-455. Go to original source... Go to PubMed...
  22. Van Arsdalen KN, Barnes RW, Clarke G, et al. Deep vein thrombosis and prostatectomy. Urology 1983; 21: 461-463. Go to original source... Go to PubMed...
  23. Neudecker J, Sauerland S, Neugebauer E, et al. The European Association for Endoscopic Surgery clinical practice guideline on the pneumoperitoneum for laparoscopic surgery. Surg Endosc 2002; 16: 1121-1143. Go to original source... Go to PubMed...
  24. Caprini JA, Botteman MF, Stephens JM, et al. Economic burden of long-term complication of deep vein thrombosis after total hip replacement surgery in the United states. Value Health 2003; 6: 59-74. Go to original source... Go to PubMed...




Urology for Practice

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.