Urolog. pro Praxi, 2006; 4: 162-163

LATE ONSET HYPOGONADISM AND THE PROSTATE

MUDr. Ján Štefančík¹, MUDr. Jozef Dubravický¹, MUDr. Milan Biaško¹, prof. MUDr. Ján Breza DrSc²

¹ Urologická klinika FNsP Bratislava

² Urologická klinika LF UK, Bratislava

Increasing incidence of late onset hypogonadism (LOH) and prostate cancer & benign prostatic hyperplazia occur in parallel in men of the same age categories.When testosteron supplementation is suggested, specific aspects of prostate diseases must be considered.

Our diagnostics of late onset hypogonadism was based on subjective symptoms and objective signs assessment, including appropriate laboratory evaluation (hormonal profile, PSA, liver enzymes etc.). Digital rectal examination and PSA evaluation were mandatory before starting testosterone supplementation.Patients were checked quarterly in the first year of treatment and anually later. If one of these tests was positive, prostate biopsy was indicated.We strictly respected suspicious prostate cancer and mammary gland cancer as absolute contraidications for testosterone administration.

Keywords: Key words: PADAM (Partial androgen deficiency in aging men), LOH, aging, testosterone, androgen replacement therapy, prostate cancer.

Published: January 1, 2007  Show citation