Urolog. pro Praxi, 2002; 6: 258-259

Molekulární biologie v onkologii prostaty aneb kudy vede cesta

MUDr. Roman Staněk
Urologické oddělení, Slezská nemocnice, Opava

Keywords: apoptosis, carcinoma of the prostate, therapy, bcl-2, endothelin.

Published: December 31, 2002  Show citation

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Staněk R. Molekulární biologie v onkologii prostaty aneb kudy vede cesta. Urol. praxi. 2002;3(6):258-259.

V současnosti dochází k ohromnému rozvoji genových metod. S rozvojem výzkumu narůstá objem znalostí využitelných v diagnostice a terapii. Jednou z nejprobádanějších oblastí v uroonkologii je karcinom prostaty, u něhož se genovými metodami dospělo již do oblasti tvorby farmaceutických přípravků. Zatím je plánované jejich využití hlavně v oblasti hormonálně rezistentního karcinomu prostaty (HR-CaP). V nejbližších letech lze očekávat i další rozvoj genové terapie a není vyloučeno, že se již naše generace bude běžně s těmito postupy setkávat. Proto podávám orientační přehled jejich současných možností.

Molecular biology in prostatic oncology and or where is the way

Today genetic methods are in the grand development. The volume of the knowledges is growing with development of the research from diagnostic methods to therapy. One of the best known area of urooncology is carcinoma of the prostate. Genetics methods should play important role at pharmacology of the prostate carcinoma. For the present time genetic phramacology utility is plan for hormonal resistent carcinoma of the prostate (HR-CaP). We can expect additional development of gen therapy and it could be at the time of current urologists. Therefore I submit review of current possibilies of gen therapy of prostate carcinoma.

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