Urolog. pro Praxi, 2002; 4: 142-149

Diagnostika karcinomu prostaty - současné možnosti a limitace transrektální ultrazvukem vedené biopsie prostaty

MUDr. Aleš Čermák1, doc. MUDr. Dalibor Pacík CSc2
1 Urologická klinika FN Brno
2 Přednosta urologické kliniky FN Brno LF Masarykovy Univerzity Brno

Keywords: prostate cancer, guided needle biopsy of the prostate, transrectal ultrasonography.

Published: December 31, 2002  Show citation

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Čermák A, Pacík D. Diagnostika karcinomu prostaty - současné možnosti a limitace transrektální ultrazvukem vedené biopsie prostaty. Urol. praxi. 2002;3(4):142-149.

U pacientů s podezřením na karcinom prostaty je indikována ultrazvukem vedená biopsie prostaty k získání vzorků tkáně prostaty pro histologické vyšetření. Technika sextantové biopsie se stala -zlatým standardem- v diagnostice karcinomu prostaty. Ukazuje se však, že sextantová biopsie má svá omezení, protože nedetekuje určitou část signifikantních karcinomů. Optimální počet vzorků potřebných k detekci těchto nádorů není zatím znám. Strategie zvýšení počtu odebíraných vzorků a nová schémata rozmístění vzorků mohou snížit počet nesprávně negativních výsledků. Tématem sdělení je sledování nedostatků jednotlivých technik v detekci karcinomu prostaty a snaha o optimalizaci metody biopsie prostaty.

Diagnostics of prostatic cancer - current possibilities and limitations of transrectal ultrasound guided needle biopsy of the prostate

Transrectal ultrasonography guided needle biopsy of the prostate has become the procedure of choice for obtaining high-quality tissue cores for histopatological assessment in the patients with suspected prostate cancer. The sextant method has become widely accepted as the -gold standard- biopsy technique. However, concern has arisen that the sextant biopsy method under-samples the prostate and consequently may fail to detect a significant proportion of clinically important tumours. It is uncertain how many biopsy cores are needed to optimize the detection of these tumors. Improved glandular coverage, by either taking more biopsies per gland and/or optimalization of the systematic biopsy scheme, should minimize sampling inacuracy. The sampling error of current prostatic biopsy techniques is a matter of concern.

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